The Frequency Of Breast Tumor In Liguria Biology Essay

Incidence of breast tumor in

Liguria from 1970- 2010

Federico Guasone

International school of Genoa

Candidate Code: 1380-008

Index

Introduction……….. pag. 3

Incidence 1970-1980……….. pag.4-8

Incidence 1981-1990………..pag.9-12

Incidence 1991-2000……….. pag.13-16

Incidence 2001-2010………..pag. 17-20

Mean of incidence……….. pag.21

Conclusion and Bibliography………..pag.22

Introduction

Area of interest: Breast tumor

Topic: The frequency of breast tumor in Liguria

Reason of choice: I love this topic and I would like to become a doctor and discover how many people can get a breast tumor.

Statement of task: Firstly, I will research on reliable medical sites to discover the frequency of getting a breast tumor. Secondly, I will make calculations and I will draw frequency graphs to demonstrate how many people can get a breast tumor.

Overall plan:

I will make an introduction by explaining the causes and the effects of tumor and I will describe the breast tumor

I will search my data and collect from 1970 to 2010

I will analyze my data and I will produce bar graphs and I will calculate the frequency of the incidence of the tumor

In conclusion I will evaluate my data and graphs.

Source of data collection: I will take the data from http://www.tumori.net/it3/banca_dati/query.php

Mathematical processes: I will calculate the mean of the incidence of tumor by calculating the average of the incidence every 10 years, then I will calculate the standard deviation of the incidence by showing how the data are spread above and below the mean, finally I will demonstrate the frequency of the tumor by using frequency graphs.

Introduction

Breast cancer is an uncontrolled division of breast cells. Cancer can result from a mutation or from an abnormality in a gene which controls the growth of cells. Mutation can switch on or switch off some gene , and this causes the uncontrolled division of cells. Breast cancer is a malignant tumor, this means that the tumor expand to other healthy cells and infects them. The cancer may start in the lobules of the breast( milk glands), or in the duct(passage that transports milk from the lobules to the nipple). 90% of all the breast cancer is due to genetic modifications . Women can reduce the possibilities of having a breast cancer by having a healthy life and by avoiding smoking, alcohol and drugs which are the causes of different types of tumor. In this project, I will analyze the average and the frequencies of getting a breast cancer. I will analyze this topic by plotting frequency graphs.

We will divide the data about tumors in Liguria in every 10 years from 1970 to 2010 .

Incidence of the tumor between 1970-1980

Age

Incidence of the tumor among women

1970

20-24

1

25-29

5

30-34

13

35-39

26

40-44

45

45-49

66

50-54

58

55-59

87

60-64

87

65-69

79

70-74

67

75-79

55

80-84

40

1971

20-24

2

25-29

5

30-34

14

35-39

27

40-44

47

45-49

67

50-54

63

55-59

89

60-64

93

65-69

84

70-74

72

75-79

60

80-84

43

1972

20-24

2

25-29

5

30-34

14

35-39

27

40-44

48

45-49

69

50-54

72

55-59

87

60-64

99

65-69

89

70-74

78

75-79

65

80-84

47

1973

20-24

2

25-29

5

30-34

15

35-39

28

40-44

50

45-49

70

50-54

82

55-59

83

60-64

104

65-69

95

70-74

83

75-79

69

80-84

51

1974

20-24

2

25-29

5

30-34

14

35-39

30

40-44

51

45-49

73

50-54

92

55-59

79

60-64

109

65-69

101

70-74

89

75-79

73

80-84

55

1975

20-24

2

25-29

6

30-34

14

35-39

31

40-44

51

45-49

75

50-54

97

55-59

80

60-64

112

65-69

108

70-74

94

75-79

78

80-84

60

1976

20-24

2

25-29

6

30-34

14

35-39

32

40-44

52

45-49

78

50-54

99

55-59

86

60-64

113

65-69

113

70-74

99

75-79

83

80-84

64

1977

20-24

2

25-29

6

30-34

15

35-39

33

40-44

52

45-49

80

50-54

100

55-59

97

60-64

110

65-69

119

70-74

104

75-79

88

80-84

68

1978

20-24

2

25-29

6

30-34

15

35-39

33

40-44

54

45-49

81

50-54

102

55-59

110

60-64

104

65-69

125

70-74

110

75-79

93

80-84

71

1979

20-24

2

25-29

6

30-34

16

35-39

33

40-44

56

45-49

82

50-54

104

55-59

121

60-64

98

65-69

130

70-74

117

75-79

99

80-84

75

1980

20-24

2

25-29

6

30-34

16

35-39

32

40-44

58

45-49

82

50-54

108

55-59

127

60-64

98

65-69

134

70-74

124

75-79

105

80-84

80

Standard deviation: 38.002

Mean: 62,29577

This graph shows that the incidence between 1970-1980 is the lowest compared to the next years. The possibility of getting a tumor increase with the increase in age. The standard deviation shows that the data are widely spread across the mean, due to the fact that the cases of the women with tumor increase every year and the data differ for the different ages of the women.

The incidence between 1981-1990

Age

Incidence of the tumor among women

1981

20-24

2

25-29

6

30-34

17

35-39

31

40-44

60

45-49

82

50-54

110

55-59

129

60-64

106

65-69

134

70-74

130

75-79

111

80-84

85

1982

20-24

2

25-29

6

30-34

16

35-39

32

40-44

61

45-49

83

50-54

112

55-59

129

60-64

118

65-69

130

70-74

136

75-79

116

80-84

91

1983

20-24

2

25-29

6

30-34

16

35-39

33

40-44

60

45-49

85

50-54

113

55-59

130

60-64

132

65-69

121

70-74

141

75-79

122

80-84

97

1984

20-24

2

25-29

6

30-34

15

35-39

34

40-44

59

45-49

87

50-54

113

55-59

132

60-64

145

65-69

113

70-74

146

75-79

129

80-84

102

1985

20-24

2

25-29

6

30-34

15

35-39

35

40-44

57

45-49

90

50-54

113

55-59

135

60-64

150

65-69

112

70-74

150

75-79

135

80-84

108

1986

20-24

2

25-29

6

30-34

15

35-39

36

40-44

56

45-49

92

50-54

112

55-59

137

60-64

150

65-69

119

70-74

149

75-79

141

80-84

114

1987

20-24

2

25-29

7

30-34

15

35-39

34

40-44

57

45-49

92

50-54

112

55-59

138

60-64

150

65-69

132

70-74

143

75-79

146

80-84

119

1988

20-24

2

25-29

7

30-34

16

35-39

33

40-44

59

45-49

91

50-54

114

55-59

139

60-64

150

65-69

147

70-74

133

75-79

152

80-84

126

1989

20-24

2

25-29

7

30-34

16

35-39

32

40-44

60

45-49

88

50-54

117

55-59

138

60-64

152

65-69

160

70-74

123

75-79

157

80-84

133

1990

20-24

2

25-29

7

30-34

16

35-39

32

40-44

62

45-49

85

50-54

119

55-59

136

60-64

154

65-69

166

70-74

121

75-79

161

80-84

140

Standard deviation: 53,78413

Mean: 85,5

This graph shows that the mean incidence has increased from 65 to 85 from 1970-1980. The mean of the incidence has increased of 20 women with the breast cancer detected. The standard deviation shows that the data are widely spread through the mean, as before this is due to the difference of cases every year. The highest frequency of getting a tumor is from 50 to 60.

The incidence between 1991-2000

Age

Incidence of the tumor among women

1991

20-24

2

25-29

7

30-34

17

35-39

32

40-44

62

45-49

83

50-54

121

55-59

135

60-64

156

65-69

166

70-74

129

75-79

160

80-84

146

1992

20-24

2

25-29

8

30-34

17

35-39

32

40-44

59

45-49

85

50-54

121

55-59

135

60-64

157

65-69

165

70-74

143

75-79

153

80-84

153

1993

20-24

2

25-29

8

30-34

17

35-39

33

40-44

57

45-49

87

50-54

119

55-59

136

60-64

157

65-69

164

70-74

159

75-79

143

80-84

159

1994

20-24

2

25-29

7

30-34

18

35-39

33

40-44

55

45-49

88

50-54

115

55-59

139

60-64

155

65-69

165

70-74

172

75-79

132

80-84

165

1995

20-24

2

25-29

7

30-34

18

35-39

33

40-44

54

45-49

90

50-54

109

55-59

141

60-64

153

65-69

167

70-74

178

75-79

129

80-84

169

1996

20-24

2

25-29

7

30-34

19

35-39

34

40-44

54

45-49

89

50-54

106

55-59

142

60-64

150

65-69

168

70-74

177

75-79

137

80-84

167

1997

20-24

2

25-29

7

30-34

19

35-39

34

40-44

54

45-49

85

50-54

108

55-59

141

60-64

148

65-69

168

70-74

174

75-79

151

80-84

159

1998

20-24

2

25-29

7

30-34

19

35-39

35

40-44

54

45-49

81

50-54

109

55-59

137

60-64

149

65-69

167

70-74

173

75-79

166

80-84

147

1999

20-24

2

25-29

6

30-34

18

35-39

36

40-44

54

45-49

78

50-54

110

55-59

132

60-64

151

65-69

164

70-74

172

75-79

180

80-84

135

2000

20-24

1

25-29

6

30-34

18

35-39

36

40-44

55

45-49

76

50-54

112

55-59

125

60-64

153

65-69

161

70-74

174

75-79

185

80-84

132

Standard deviation: 62,35764

Mean: 97

The mean of the incidence has increased from 85 to 97 from 1980. The mean has increased, but less than from 1970 to 1990. The standard deviation shows that the data are widely spread due to the big quantity of data. The highest chance of getting a tumor is from 50 to 70.

The incidence between 2001-2010

Age

Incidence of the tumor among women

2001

20-24

1

25-29

6

30-34

17

35-39

37

40-44

55

45-49

76

50-54

110

55-59

121

60-64

154

65-69

158

70-74

175

75-79

184

80-84

141

2002

20-24

1

25-29

6

30-34

17

35-39

37

40-44

56

45-49

76

50-54

105

55-59

123

60-64

153

65-69

156

70-74

175

75-79

183

80-84

156

2003

20-24

1

25-29

5

30-34

17

35-39

37

40-44

58

45-49

77

50-54

101

55-59

126

60-64

149

65-69

158

70-74

176

75-79

183

80-84

174

2004

20-24

1

25-29

5

30-34

16

35-39

37

40-44

60

45-49

78

50-54

99

55-59

128

60-64

144

65-69

161

70-74

174

75-79

185

80-84

189

2005

20-24

1

25-29

5

30-34

16

35-39

37

40-44

62

45-49

80

50-54

98

55-59

130

60-64

137

65-69

163

70-74

171

75-79

187

80-84

197

2006

20-24

1

25-29

4

30-34

16

35-39

37

40-44

64

45-49

82

50-54

97

55-59

129

60-64

133

65-69

164

70-74

167

75-79

187

80-84

196

2007

20-24

1

25-29

4

30-34

15

35-39

36

40-44

65

45-49

84

50-54

99

55-59

123

60-64

136

65-69

163

70-74

165

75-79

188

80-84

195

2008

20-24

1

25-29

4

30-34

14

35-39

35

40-44

65

45-49

86

50-54

100

55-59

118

60-64

138

65-69

158

70-74

167

75-79

187

80-84

195

2009

20-24

1

25-29

4

30-34

14

35-39

35

40-44

65

45-49

89

50-54

102

55-59

116

60-64

141

65-69

152

70-74

170

75-79

185

80-84

196

2010

20-24

1

25-29

4

30-34

13

35-39

34

40-44

63

45-49

91

50-54

103

55-59

114

60-64

143

65-69

145

70-74

172

75-79

182

80-84

200

Mean: 97,35385

Standard deviation: 66,71946

The incidence of getting a tumor has increased slightly from 1990. This is due to the fact that there were not great change in the possible causes of the cancer(ex. radiation), that caused the mean to change so drastically. The standard deviation is high, this demonstrates that the data are widely spread across the mean.

Mean Graph from 1970 to 2010

There is an increase of the incidence every year. The mean in 1970 was 62.3, instead in 2010 the mean was about 97.4. There is a linear increase in the incidences. This could be due to factor that had changed the environment like the increase in pollution and radiation, these factors could have affected the chance of getting a tumor.

Conclusion

In conclusion, the graphs and the mean had demonstrated that the frequency of getting a tumor is rising every year. The target age of the tumor is between 50 and 80 years old. In the future, we could try to solve this problem by reducing the pollution and the emission of radiation around the world.